In a recent survey by Pew Research, close to 8 in 10 Americans believe that prescription drug prices are unreasonable, and many would support legislation to lower them. But what determines the cost of prescription drugs in the first place, and how much do Americans really pay for these medications? New named drugs on the market for less than two years are the largest contributors to spending growth. These are specialty products derived from living cells, which account for 33% of drug costs but less than 2% of prescriptions. (Used for cancer and autoimmune diseases.) Increases in the prices of brand drugs with no generic competitors also contribute to the rise of spending. Americans are using more prescription drugs. In 2016, 4.5 million prescriptions were dispensed in the U.S., a 7 percent increase since 2011 (with about half taking at least one drug.) Americans over 50 use more prescription drugs which accounts for 35% of the population but 70% of all dispensed prescriptions. However, drug spending is a complex issue that involves a range of products, policies, and stakeholders across the health care system.Related: The Top 10 Expensive Medications in Medicare Part DIn 2017, the average out-of-pocket spending on prescription drugs was $137 across all ages an insurance types. It's expected to rise to $190 by 2026. This is an average, and what patients pay varies by health plan.A 2016 Kaiser Family Foundation poll found that 44% of respondents worried about affording the cost of their prescriptions.Out-of-pocket costs are a challenge for Medicare beneficiaries. In 2015, patients reaching the catastrophic coverage phase of Medicare's drug benefit paid an average of $257/month.Get my newsletter. Send an email to Carol@seniorcare.com with newsletter in the subject line.