The Kade Spade death is quite concerning.
On one hand everyone is shocked that such a seemingly impressive person could have such great problems. On the other hand, we must learn to be more sensitive to the stress and issues facing ourselves and others. What makes it more difficult is that they sometimes withdraw and hide the issues facing them. Thus, it is sometimes more difficult to help than we realize. There do seem to be some common suggested solutions.
Related: Stress, Anxiety and Panic Disorder: What’s the Difference and What Can I Do About It?